By Alexandre A. Shvartsburg

Over the decade, medical and engineering pursuits were moving from traditional ion mobility spectrometry (IMS) to box uneven waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry: Nonlinear Ion delivery and basics of FAIMS explores this new analytical know-how that separates and characterizes ions by means of the adaptation among their mobility in gases at low and high electrical fields. It additionally covers the radical issues of higher-order differential IMS and IMS with alignment of dipole direction.

The publication relates the basics of FAIMS and different nonlinear IMS the right way to the physics of gas-phase ion delivery. It starts with the fundamentals of ion diffusion and mobility in gases, overlaying the most attributes of traditional IMS which are appropriate to all IMS techniques. construction in this starting place, the writer studies assorted high-field delivery phenomena that underlie differential IMS. He discusses the conceptual implementation and first-principles optimization of FAIMS as a filtering approach, emphasizing the dependence of FAIMS functionality metrics on instrumental parameters and houses of ion species. He additionally explores ion reactions in FAIMS brought on by box heating and the consequences of inhomogeneous electrical box in curved FAIMS gaps.

Written through an finished scientist within the box, this cutting-edge e-book provides the root to appreciate the recent know-how of nonlinear IMS methods.

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